What is HD chorea?
Individual results may vary. Xenazine may not be effective in reducing choreic movements in all HD patients. Please review the Important Safety Information, including Boxed Warning about the increased risk of depression and suicidality, below.
Chorea (kor-EE-uh) is the most visible feature of Huntington’s disease (HD), a genetic disorder affecting the brain. Nine out of ten people with HD will develop chorea at some point as their illness progresses.2
Chorea associated with HD causes involuntary movements, or movements that are not made on purpose.3 People with HD chorea may not be aware of their uncontrolled movements.4 In some people, chorea may begin before they know they have Huntington’s disease. If their chorea is mild, they may be able to hide their involuntary movements with voluntary movements.3,4 However, when they are distracted, stressed, or anxious, their chorea tends to get worse and more noticeable.3
University of Alabama at Birmingham
Huntington's Disease Center of Excellence
HD chorea can appear as jerky, twisting, writhing or dance-like motions, and people may appear to be restless, fidgety, or clumsy.5,6 Early in the disease, the movements may involve only the hands and feet. However, everyone’s story is different. Eventually the face, neck, shoulders, trunk, and legs may be affected.3
HD chorea symptoms usually appear between ages 30 and 54, although 10% of symptoms can develop after age 60.3,7 It is important to note that one person’s HD chorea does not necessarily begin the same as someone else’s and some people may not even experience chorea associated with HD.2,4
Ask your doctor about a treatment that might help lessen HD chorea. It is helpful while asking your doctor about a treatment to describe the challenges you or your loved one may be facing because of HD chorea.